A set of notebooks recording biochemical research carried out by Reginald Hems (1922-2009), research assistant to Hans Adolf Krebs. Fifteen of the eighteen notebooks in the collection document biochemical research carried out by Reg Hems, research assistant to the Nobel Laureate Professor Sir Hans Krebs, between the years 1946-1984. They cover the period when Hems worked with Krebs at the Universities of Sheffield and Oxford. Of the remaining three notebooks, one is written by Leonard V. Eggleston (see the entry for the Eggleston Notebooks for further information), and the other two relate to the work of Barrie Tyler, who collaborated with Hems, in 1975, and Guillermo Saez Tormo, who worked in Krebs´ laboratory with Hems for a year from May 1981.